There are many differentiators between a VxRail™ cluster implemented on a standard network infrastructure and one implemented on a network infrastructure placed under the control of Dell EMC SmartFabric Services (SFS). These differentiators impact the decision points to be made on the physical and logical settings and administrative considerations for the VxRail cluster. This guide discusses those essential data center and networking details for a VxRail cluster implementation with an integrated network infrastructure based on Dell EMC SFS. This guide has been prepared for anyone involved in planning and implementation efforts of a VxRail cluster on a network infrastructure based on Dell EMC SFS, including Dell EMC field engineers, customer system and network administrators, and IT personnel. It should be used for planning and preparation purposes only. It introduces requirements, best practices, and recommendations for both physical and virtual network environments. It should not be used to perform the actual installation and set-up of VxRail cluster or the underlying network infrastructure. Work with your Dell EMC service representative to perform the actual planning and design for the overall solution, and the subsequent implementation effort.