Secured-Core is a Windows Server security feature available in Windows Server 2022 and Azure Stack HCI OS 21H2. Enabling Secured-Core involves modifying BIOS and operating system level settings.
The AX-7525 (with AMD Epic 7xx3 Milan CPUs), AX-650, and AX-750 platforms support the required BIOS settings to enable the Secured-Core feature. Also, each of these platforms ship with the required TPM 2.0 v3 hardware installed from the factory.
You can enable operating system-level settings using Windows Admin Center.
To enable Secured-Core, see Managing and Monitoring the Solution Infrastructure Life Cycle Operations Guide