Data center consolidation through server virtualization has gained tremendous momentum and offers many benefits such as flexibility, effective utilization of compute resources, reduction in data center footprint and management overhead, and so on. Even though servers are virtualized, the necessity of data protection remains. Virtualization unlocks new and flexible opportunities in data protection, data recovery, replication, and business continuity. With PowerFlex 3.6 release, a PowerFlex Storage Replication Adapter (SRA) is introduced that enables VMware Site Recovery Manager to interact with a PowerFlex storage environment. This document offers guidelines and best practices for automated disaster recovery of virtualized workloads using PowerFlex, native asynchronous replication, PowerFlex SRA, and SRM.