This document describes the business challenge, approach, and benefits of implementing an efficient infrastructure for the sharing of GPU resources for both VDI and AI workloads in a healthcare environment. The guide describes the solution architecture and the key hardware and software components of the architecture, and provides guidance on designing, managing, and scaling a shared VMware Horizon 8 environment on Dell EMC VxRail. It also summarizes the performance testing that the Dell Technologies VDI Solutions team performed and describes possible extensions to the architecture such as storage options.