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The backend network between the PowerEdge nodes and PowerScale should be a minimum of 25 Gbps with Jumbo Frames set (MTU=9162) for the NICs and the switch ports.
net.ipv4.tcp_timestamps=0
net.ipv4.tcp_sack=1
net.core.netdev_max_backlog=250000
net.core.rmem_max=4194304
net.core.wmem_max=4194304
net.core.rmem_default=4194304
net.core_wmem_default=4194304
net.core.optmem_max=4194304
net.ipv4.tcp_rmem=4096 87380 4194304
net.ipv4.tcp_wmem=4096 65536 4194304